Best for: stateful long-running agents with fine control
Low-level orchestration framework from LangChain for building stateful agents as graphs with durable execution.
StandoutDurable execution that recovers from failures
Watch out forLow-level API takes time to learn
- Starting price
- Free (open source)
- Free trial
- Free LangSmith tier
- Languages
- Python, JavaScript/TypeScript
Best for: role-based multi-agent teams and workflows
Python framework for running teams of role-based AI agents as crews, with event-driven Flows for workflow control.
StandoutSimple role and task model for multi-agent teams
Watch out forPython only (3.10 to 3.13)
- Starting price
- Free (open source)
- Free trial
- Free AMP Basic plan
- Languages
- Python
Best for: lightweight multi-agent apps with handoffs
Lightweight open-source framework from OpenAI for multi-agent workflows with handoffs, guardrails and built-in tracing.
StandoutSmall set of building blocks, easy to learn
Watch out forDefaults and best support are for OpenAI models
- Starting price
- Free (open source)
- Languages
- Python, JavaScript/TypeScript
Best for: agents that read files, run commands and edit code
Anthropic's SDK that packages Claude Code's tools, agent loop and context management as a Python or TypeScript library.
StandoutBuilt-in tools for files, shell and web search
Watch out forWorks with Claude models only
- Starting price
- Free SDK; pay for Claude API use
- Languages
- Python, TypeScript
Best for: .NET and Python teams building production agents
Open-source Microsoft framework for agents and multi-agent workflows, and the successor to AutoGen and Semantic Kernel.
StandoutSuccessor to AutoGen and Semantic Kernel, with migration guides
Watch out forGo version is in preview and missing features
- Starting price
- Free (open source)
- Languages
- C# (.NET), Python, Go (preview)
Best for: multi-language agents with easy Google Cloud deployment
Google's open-source, code-first toolkit for building, testing and deploying agents in Python, TypeScript, Go, Java and Kotlin.
StandoutFive language SDKs with a consistent API
Watch out forDeployment guides center on Google Cloud
- Starting price
- Free (open source)
- Languages
- Python, TypeScript, Go, Java, Kotlin
Best for: document-heavy agents and RAG in Python
Open-source Python toolkit for building LLM agents and event-driven workflows over your own documents and data.
StandoutDeep tooling for document ingestion, retrieval and RAG
Watch out forTypeScript version was deprecated in April 2026
- Starting price
- Free (open source); LlamaParse from $50/mo
- Free trial
- Free LlamaParse plan
- Languages
- Python
Best for: typeScript developers building agents into web apps
Open-source TypeScript framework for AI agents and workflows with memory, tools, evals and a local Studio.
StandoutNative TypeScript with Next.js, React, Express and Hono integrations
Watch out forTypeScript/JavaScript only; needs Node.js 22.18 or later
- Starting price
- Free (open source); Cloud Teams $250/mo
- Free trial
- Free Mastra Cloud Starter
- Languages
- TypeScript, JavaScript